Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29098918 | 0.92 | SMN1; SMN2 (0.45) | HPGDKDM4ESMN1; SMN2NPC1LMNA | |
| SCHEMBL29098920 | 0.89 | SMN1; SMN2 (0.45) | HPGDSMN1; SMN2NPC1LMNARAB9A | |
| SCHEMBL3720178 | 0.87 | HPGD (0.46) | HPGDKDM4ESMN1; SMN2NPC1LMNA | |
| SCHEMBL7928370 | 0.84 | HPGD (0.60) | HPGDKDM4ESMN1; SMN2NPC1LMNA | |
| SCHEMBL4704298 | 0.80 | MAPK1 (0.43) | HPGDSMN1; SMN2LMNAMAPTSLC6A4 | |
| SCHEMBL14121850 | 0.80 | SLC7A5 (0.38) | KDM4ESMN1; SMN2LMNARAB9ASLC6A4 | |
| SCHEMBL7931152 | 0.80 | HPGD (0.55) | HPGDKDM4ESMN1; SMN2NPC1LMNA | |
| SCHEMBL13010769 | 0.80 | HPGD (0.55) | HPGDKDM4ESMN1; SMN2NPC1LMNA | |
| SCHEMBL18704596 | 0.79 | S1PR4 (0.54) | HPGDKDM4ESMN1; SMN2NPC1LMNA | |
| SCHEMBL12144470 | 0.78 | AAK1 (0.42) | SLC6A4HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114230552-B | Trifluoromethoxy dibenzothiophene, preparation method thereof and preparation method of related intermediate | 江苏广域化学有限公司 | 2023-11-03 | — | — | CN | disclosed |
| CN-114230552-A | Trifluoromethoxy dibenzothiophene, preparation method thereof and preparation method of related intermediate | 江苏广域化学有限公司 | 2022-03-25 | — | — | CN | disclosed |