Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | KLKB1 | P03952 | 4/20 | 0.43 |
| ▸ | IL4I1 | Q96RQ9 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KLK1 | P06870 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7081463 | 0.83 | LMNA (0.49) | MAPTLMNAPOLBNPSR1KMT2A | |
| SCHEMBL12639949 | 0.83 | LMNA (0.50) | LMNAALDH1A1POLBNPSR1KMT2A | |
| SCHEMBL9752676 | 0.82 | POLB (0.58) | MAPTLMNAALDH1A1L3MBTL1POLB | |
| SCHEMBL27552118 | 0.81 | PLAU (0.58) | POLBNPSR1 | |
| SCHEMBL3807659 | 0.80 | PDE4B (0.43) | KLKB1 | |
| SCHEMBL12640061 | 0.79 | MAPK14 (0.52) | LMNAMAOBHTTCYP2D6BRD4 | |
| SCHEMBL13932944 | 0.78 | POLB (0.50) | MAPTLMNAPOLBNPSR1KLKB1 | |
| SCHEMBL14611520 | 0.78 | MAPT (0.57) | MAPTLMNAALDH1A1POLBNPSR1 | |
| SCHEMBL28105676 | 0.78 | KMT2A (0.49) | MAPTPOLBNPSR1KMT2AKLKB1 | |
| SCHEMBL16891555 | 0.77 | KLKB1 (0.44) | LMNAKMT2AKLKB1KLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111170991-B | Antiproliferative compounds and methods of synthesis thereof | 细胞基因公司 | 2023-10-31 | — | — | CN | disclosed |