Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 5/20 | 0.39 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.33 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 3/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | MGLL | Q99685 | 1/20 | 0.31 |
| ▸ | GRB2 | P62993 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | RBP4 | P02753 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17420649 | 0.84 | RXRA (0.41) | PPARGL3MBTL1 | |
| SCHEMBL30628201 | 0.84 | RXRA (0.41) | PPARGL3MBTL1 | |
| SCHEMBL29099254 | 0.81 | MAPT (0.39) | PPARGTSHRL3MBTL1EPHX2 | |
| SCHEMBL30628189 | 0.80 | EPHX2 (0.44) | PPARGKCNN4MRGPRX4PKMEPHX2 | |
| SCHEMBL17420667 | 0.80 | EPHX2 (0.44) | PPARGKCNN4MRGPRX4PKMEPHX2 | |
| SCHEMBL17420416 | 0.75 | RXRA (0.42) | PPARGMRGPRX4PKMTSHRTDP1 | |
| SCHEMBL30628312 | 0.75 | RXRA (0.42) | PPARGMRGPRX4PKMTSHRTDP1 | |
| SCHEMBL17420746 | 0.75 | MEN1 (0.43) | PPARGMRGPRX4PKMKDM4ENPSR1 | |
| SCHEMBL17420624 | 0.72 | KCNN4 (0.51) | KCNN4KDM4E | |
| SCHEMBL30628289 | 0.72 | KCNN4 (0.51) | KCNN4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111170991-B | Antiproliferative compounds and methods of synthesis thereof | 细胞基因公司 | 2023-10-31 | — | — | CN | disclosed |