Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | RXRB | P28702 | 1/20 | 0.41 |
| ▸ | RXRG | P48443 | 1/20 | 0.41 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.40 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.37 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.37 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | EIF4E | P06730 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17420649 | 1.00 | RXRA (0.41) | RXRARXRBRXRGKCNK3KCNK9 | |
| SCHEMBL30087653 | 0.87 | IRAK4 (0.43) | RXRARXRBRXRGKCNK3KCNK9 | |
| SCHEMBL29099261 | 0.84 | PPARG (0.39) | PPARGL3MBTL1 | |
| SCHEMBL17420685 | 0.83 | PPARG (0.49) | RXRARXRBRXRGKCNK3KCNK9 | |
| SCHEMBL30628295 | 0.83 | PPARG (0.49) | RXRARXRBRXRGKCNK3KCNK9 | |
| SCHEMBL17420436 | 0.82 | MAPT (0.41) | RXRARXRBRXRGKCNK3KCNK9 | |
| SCHEMBL17420667 | 0.81 | EPHX2 (0.44) | RXRARXRBRXRGKCNK3KCNK9 | |
| SCHEMBL30628189 | 0.81 | EPHX2 (0.44) | RXRARXRBRXRGKCNK3KCNK9 | |
| SCHEMBL24176727 | 0.80 | DRD2 (0.45) | RXRARXRBRXRGKCNK3KCNK9 | |
| SCHEMBL17420416 | 0.79 | RXRA (0.42) | RXRARXRBRXRGKCNK3KCNK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111170991-B | Antiproliferative compounds and methods of synthesis thereof | 细胞基因公司 | 2023-10-31 | — | — | CN | disclosed |