Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 3/20 | 0.67 |
| ▸ | DRD2 | P14416 | 3/20 | 0.67 |
| ▸ | ABCB1 | P08183 | 6/20 | 0.56 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.55 |
| ▸ | ELANE | P08246 | 4/20 | 0.54 |
| ▸ | F2 | P00734 | 1/20 | 0.54 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30628475 | 1.00 | HTR1A (0.67) | HTR1ADRD2ABCB1ABCG2ELANE | |
| SCHEMBL8676962 | 0.87 | ELANE (0.52) | HTR1ADRD2ABCB1ABCG2ELANE | |
| SCHEMBL6702536 | 0.87 | ELANE (0.52) | HTR1ADRD2ELANEF2SLC2A1 | |
| SCHEMBL8757373 | 0.85 | ELANE (0.71) | HTR1ADRD2ELANEF2SLC2A1 | |
| SCHEMBL31555136 | 0.83 | ABCB1 (0.58) | ABCB1ABCG2 | |
| SCHEMBL1894477 | 0.83 | ELANE (0.58) | HTR1ADRD2ELANEF2LMNA | |
| SCHEMBL8406943 | 0.82 | HTR1A (0.65) | HTR1ADRD2ABCB1ABCG2LMNA | |
| SCHEMBL12707582 | 0.82 | HTR1A (0.65) | HTR1ADRD2ABCB1ABCG2MAPT | |
| SCHEMBL8406440 | 0.81 | PTGER1 (0.63) | HTR1ADRD2ABCB1MEN1TP53 | |
| SCHEMBL8321346 | 0.81 | PTGER1 (0.77) | ELANEF2HPGDPTGER1PTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112424159-B | Novel P62 ligand compound and composition for preventing, improving or treating protein conformational diseases comprising the same | 普罗泰克株式会社 | 2023-10-31 | — | — | CN | disclosed |