SCHEMBL1894477

SCHEMBL1894477

CCc1cc(O)ccc1OCc1ccccc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 4/20 0.58
F2 P00734 1/20 0.58
CTSG P08311 1/20 0.55
MAPT P10636 3/20 0.50
TDP1 Q9NUW8 3/20 0.50
L3MBTL1 Q9Y468 3/20 0.50
LMNA P02545 3/20 0.50
HPGD P15428 2/20 0.50
GAA P10253 2/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
KDM4E B2RXH2 2/20 0.50
MEN1 O00255 1/20 0.50
ALDH1A1 P00352 1/20 0.50
TP53 P04637 1/20 0.50
THRB P10828 1/20 0.50
BLM P54132 1/20 0.50
KMT2A Q03164 1/20 0.50
NPC1 O15118 1/20 0.50
RAB9A P51151 1/20 0.50
CYP2C19 P33261 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6702536 0.87 ELANE (0.52) ELANEF2CTSGMAPTTDP1
SCHEMBL8757373 0.85 ELANE (0.71) ELANEF2CTSGMAPTTDP1
SCHEMBL30628475 0.83 HTR1A (0.67) ELANEF2CTSGMAPTTDP1
SCHEMBL29099302 0.83 HTR1A (0.67) ELANEF2CTSGMAPTTDP1
SCHEMBL12594164 0.82 CYP19A1 (0.53) MAPTTDP1L3MBTL1LMNAHPGD
SCHEMBL3724781 0.82 CCR5 (0.66) LMNASMN1; SMN2ALDH1A1RAB9ACYP1A2
SCHEMBL19987598 0.81 CDK4 (0.48) ELANEF2MAPTL3MBTL1GAA
SCHEMBL8676962 0.81 ELANE (0.52) ELANEF2CTSGMAPTTDP1
SCHEMBL8728948 0.80 SLC2A1 (0.59) ELANEF2MAPTTDP1L3MBTL1
SCHEMBL29721165 0.80 SLC2A1 (0.59) ELANEF2MAPTTDP1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1813594-B1 POLYMERIZABLE COMPOUND AND COMPOSITION CONTAINING THE POLYMERIZABLE COMPOUND ADEKA CORP (JP) 2011-05-11 EP disclosed
CN-101052613-B Polymerizable compound and composition containing same ADEKA CORP 2011-04-13 CN disclosed
US-7683203-B2 Polymerizable compound and composition containing the polymerizable compound ADEKA CORPORATION (JP) 2010-03-23 US disclosed
US-7683203-B2 Polymerizable compound and composition containing the polymerizable compound ADEKA CORPORATION (JP) 2010-03-23 US disclosed
US-20070282087-A1 Polymerizable Compound And Composition Containing The Polymerizable Compound ADEKA CORPORATION (JP) 2007-12-06 US disclosed
US-20070282087-A1 Polymerizable Compound And Composition Containing The Polymerizable Compound ADEKA CORPORATION (JP) 2007-12-06 US disclosed
US-20070282087-A1 Polymerizable Compound And Composition Containing The Polymerizable Compound ADEKA CORPORATION (JP) 2007-12-06 US disclosed
CN-101052613-A Polymerizable compound and composition containing same ADEKA CORP (JP) 2007-10-10 CN disclosed
EP-1813594-A1 POLYMERIZABLE COMPOUND AND COMPOSITION CONTAINING THE POLYMERIZABLE COMPOUND Adeka Corporation (JP) 2007-08-01 EP disclosed
EP-1813594-A1 POLYMERIZABLE COMPOUND AND COMPOSITION CONTAINING THE POLYMERIZABLE COMPOUND Adeka Corporation (JP) 2007-08-01 EP disclosed
EP-0757982-B1 Biphenylic compounds, process for their preparations and intermediates for this process, their use as 5-alpha-reductase inhibitors and pharmaceutical compositions containing them HOECHST MARION ROUSSEL INC (FR) 2000-09-20 EP disclosed
US-5965763-A Biphenyl compounds HOECHST MARION ROUSSEL (FR) 1999-10-12 US disclosed
US-5827887-A 5-ALPHA REDUCTASE INHIBITORS ROUSSEL UCLAF (FR) 1998-10-27 US disclosed
EP-0757982-A1 Biphenylic compounds, process for their preparations and intermediates for this process, their use as 5-alpha-reductase inhibitors and pharmaceutical compositions containing them ROUSSEL UCLAF (FR) 1997-02-12 EP disclosed