Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28670873 | 0.98 | L3MBTL1 (0.44) | THRBATML3MBTL1GAARAB9A | |
| SCHEMBL6248598 | 0.85 | SMN1; SMN2 (0.44) | ATML3MBTL1RAB9AALDH1A1POLB | |
| SCHEMBL20663620 | 0.80 | DPP4 (0.40) | L3MBTL1POLB | |
| SCHEMBL13532420 | 0.79 | RAB9A (0.43) | THRBATML3MBTL1GAARAB9A | |
| SCHEMBL12133179 | 0.79 | RAB9A (0.43) | THRBATML3MBTL1GAARAB9A | |
| SCHEMBL15730209 | 0.78 | RAB9A (0.45) | THRBATML3MBTL1GAARAB9A | |
| SCHEMBL9732326 | 0.78 | RAB9A (0.45) | THRBATML3MBTL1GAARAB9A | |
| SCHEMBL15274970 | 0.78 | RAB9A (0.45) | THRBATML3MBTL1GAARAB9A | |
| SCHEMBL2684345 | 0.77 | HSD17B10 (0.50) | ALDH1A1 | |
| SCHEMBL4244079 | 0.77 | HSD17B10 (0.50) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111801100-B | 7-substituted sulfoimidoyl purinone compounds and derivatives for the treatment and prevention of liver cancer | 豪夫迈·罗氏有限公司 | 2023-10-24 | — | — | CN | disclosed |