Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 2/20 | 0.47 |
| ▸ | CTSA | P10619 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30185560 | 1.00 | KCNA5 (0.47) | KCNA5CTSAALDH1A1CNR1L3MBTL1 | |
| SCHEMBL2502376 | 0.84 | HIF1A (0.41) | — | |
| SCHEMBL2498782 | 0.84 | HIF1A (0.41) | — | |
| SCHEMBL13882059 | 0.84 | HIF1A (0.41) | — | |
| SCHEMBL2500312 | 0.83 | L3MBTL1 (0.51) | ALDH1A1L3MBTL1 | |
| SCHEMBL30185583 | 0.82 | CTSA (0.47) | CTSAALDH1A1 | |
| SCHEMBL29099531 | 0.82 | CTSA (0.47) | CTSAALDH1A1 | |
| SCHEMBL3652941 | 0.82 | KCNA5 (0.47) | KCNA5ALDH1A1L3MBTL1 | |
| SCHEMBL8770921 | 0.80 | KCNA5 (0.50) | KCNA5L3MBTL1 | |
| SCHEMBL24661003 | 0.78 | KCNA5 (0.52) | KCNA5CTSAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115611883-A | PI3K alpha inhibitor with bicyclic structure and preparation method and application thereof | 生物岛实验室 | 2023-01-17 | — | — | CN | disclosed |