Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSA | P10619 | 1/20 | 0.47 |
| ▸ | MGAM | O43451 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SI | P14410 | 1/20 | 0.41 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | FNTA | P49354 | 1/20 | 0.40 |
| ▸ | FNTB | P49356 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.38 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 2/20 | 0.37 |
| ▸ | TDO2 | P48775 | 1/20 | 0.37 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.37 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29099531 | 1.00 | CTSA (0.47) | CTSAMGAMGAASIMGAM2 | |
| SCHEMBL3658761 | 0.83 | KYNU (0.44) | GAASMN1; SMN2FFAR1IDO1GABBR2 | |
| SCHEMBL3660011 | 0.83 | KYNU (0.44) | GAASMN1; SMN2FFAR1IDO1GABBR2 | |
| SCHEMBL29099504 | 0.82 | KCNA5 (0.47) | CTSAALDH1A1 | |
| SCHEMBL30185560 | 0.82 | KCNA5 (0.47) | CTSAALDH1A1 | |
| SCHEMBL19817286 | 0.81 | GABBR2 (0.48) | FFAR1FNTAFNTBGABBR2GABBR1 | |
| SCHEMBL3053473 | 0.81 | GABBR2 (0.48) | FFAR1FNTAFNTBGABBR2GABBR1 | |
| SCHEMBL23125123 | 0.81 | ACP3 (0.50) | CTSASMN1; SMN2ALDH1A1SLC6A9IDO1 | |
| SCHEMBL1932025 | 0.81 | CPN1 (0.49) | SMN1; SMN2FFAR1IDO1GABBR2GABBR1 | |
| SCHEMBL7141329 | 0.78 | FNTA (0.53) | CTSAMGAMGAASIMGAM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024125464-A1 | TETRAHYDROISOQUINOLIN-ONE DERIVATIVES, PREPARATION METHODS AND MEDICINAL USES THEREOF | JIANGSU HANSOH PHARMACEUTICAL GROUP CO., LTD. (CN) | 2024-06-20 | — | — | WO | disclosed |
| CN-115611883-A | PI3K alpha inhibitor with bicyclic structure and preparation method and application thereof | 生物岛实验室 | 2023-01-17 | — | — | CN | disclosed |