Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 8/20 | 0.42 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.31 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.31 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.31 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.31 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.31 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.31 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29099899 | 0.89 | AURKB (0.36) | TLR8SMN1; SMN2MAPK8LMNAHPGD | |
| SCHEMBL29099897 | 0.89 | AURKB (0.36) | TLR8SMN1; SMN2MAPK8LMNAHPGD | |
| SCHEMBL29093607 | 0.81 | TLR8 (0.64) | TLR8TLR7SMN1; SMN2MAPK8LMNA | |
| SCHEMBL29093600 | 0.81 | TLR8 (0.64) | TLR8TLR7SMN1; SMN2MAPK8LMNA | |
| SCHEMBL23367234 | 0.79 | TLR8 (0.64) | TLR8TLR7 | |
| SCHEMBL21612967 | 0.79 | TLR8 (0.64) | TLR8TLR7 | |
| SCHEMBL29758962 | 0.79 | TLR8 (0.64) | TLR8TLR7 | |
| SCHEMBL29093582 | 0.76 | TLR8 (0.61) | TLR8TLR7LMNAHPGD | |
| SCHEMBL30557848 | 0.75 | TLR8 (0.45) | TLR8TLR7HDAC3HDAC1HDAC2 | |
| SCHEMBL18109610 | 0.73 | TLR8 (0.56) | TLR8TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116969934-A | Pyrimido aromatic ring compounds and application thereof in medicines | 广东东阳光药业股份有限公司 | 2023-10-31 | — | — | CN | disclosed |