Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 9/20 | 0.45 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | CLK2 | P49760 | 1/20 | 0.34 |
| ▸ | CLK3 | P49761 | 1/20 | 0.34 |
| ▸ | WNT1 | P04628 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | BRAF | P15056 | 3/20 | 0.33 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
| ▸ | WDR5 | P61964 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29093600 | 0.84 | TLR8 (0.64) | TLR8TLR7KCNH2 | |
| SCHEMBL29093607 | 0.84 | TLR8 (0.64) | TLR8TLR7KCNH2 | |
| SCHEMBL30623094 | 0.84 | TLR8 (0.40) | TLR8TLR7DYRK1ACLK2CLK3 | |
| SCHEMBL29093582 | 0.81 | TLR8 (0.61) | TLR8TLR7 | |
| SCHEMBL29093593 | 0.78 | TLR8 (0.48) | TLR8TLR7HDAC3KCNH2 | |
| SCHEMBL29093590 | 0.78 | TLR8 (0.48) | TLR8TLR7HDAC3KCNH2 | |
| SCHEMBL25377923 | 0.76 | TLR8 (0.37) | TLR8TLR7 | |
| SCHEMBL25437276 | 0.76 | TLR8 (0.37) | TLR8TLR7 | |
| SCHEMBL29099890 | 0.76 | TLR8 (0.34) | TLR8TLR7HRH4DYRK1ACLK2 | |
| SCHEMBL29099892 | 0.76 | TLR8 (0.34) | TLR8TLR7HRH4DYRK1ACLK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116768883-A | Pyrimido aromatic ring compounds and application thereof in medicines | 广东东阳光药业股份有限公司 | 2023-09-19 | — | — | CN | disclosed |