SCHEMBL4983337

SCHEMBL4983337

C=C(C)C(=O)OCCCCCCNC(=O)C(C)=O

nearest known ligand 0.59

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.59
POLB P06746 1/20 0.46
APEX1 P27695 1/20 0.46
HTT P42858 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
THRB P10828 1/20 0.43
ACHE P22303 12/20 0.42
KDM4E B2RXH2 1/20 0.39
MAPK1 P28482 1/20 0.39
HIF1A Q16665 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4977289 1.00 TSHR (0.59) TSHRPOLBAPEX1HTTTDP1
SCHEMBL4980959 0.98 TSHR (0.56) TSHRPOLBAPEX1HTTTDP1
SCHEMBL16309328 0.93 TSHR (0.62) TSHRPOLBAPEX1HTTTDP1
SCHEMBL4984517 0.93 TSHR (0.53) TSHRPOLBAPEX1HTTTDP1
SCHEMBL29100295 0.92 TSHR (0.61) TSHRPOLBAPEX1HTTTDP1
SCHEMBL29100282 0.92 TSHR (0.61) TSHRPOLBAPEX1HTTTDP1
SCHEMBL16385235 0.86 TSHR (0.62) TSHRPOLBAPEX1HTTTDP1
SCHEMBL2720550 0.86 TSHR (0.62) TSHRPOLBAPEX1HTTTDP1
SCHEMBL16384917 0.86 TSHR (0.62) TSHRPOLBAPEX1HTTTDP1
SCHEMBL4978941 0.86 THRB (0.48) TSHRPOLBAPEX1HTTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080053835-A1 Monomer Compound, Process for Producing the Same, Polymer Thereof, and Water-Based Curable Composition KANSAI PAINT CO., LTD. (JP) 2008-03-06 US disclosed
EP-1798218-A1 MONOMER COMPOUND, PROCESS FOR PRODUCING THE SAME, POLYMER THEREOF, AND WATER-BASED CURABLE COMPOSITION KANSAI PAINT CO., LTD. (JP) 2007-06-20 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080053835-A1 Monomer Compound, Process for Producing the Same, Polymer Thereof, and Water-Based Curable Composition THEM6, PAM, WEE1 TSHR 4460/4885POLB 697/4885APEX1 2898/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.