Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 1.00 |
| ▸ | GAA | P10253 | 2/20 | 1.00 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | PARP1 | P09874 | 5/20 | 0.46 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.45 |
| ▸ | IKBKB | O14920 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.44 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL634215 | 1.00 | KDM4E (1.00) | KDM4EALDH1A1GAAPDPK1KMT2A | |
| SCHEMBL29498815 | 1.00 | KDM4E (1.00) | KDM4EALDH1A1GAAPDPK1KMT2A | |
| SCHEMBL30181949 | 1.00 | KDM4E (1.00) | KDM4EALDH1A1GAAPDPK1KMT2A | |
| SCHEMBL25192670 | 0.98 | KDM4E (0.96) | KDM4EALDH1A1GAAPDPK1KMT2A | |
| SCHEMBL497724 | 0.98 | KDM4E (0.96) | KDM4EALDH1A1GAAPDPK1KMT2A | |
| Hydrochloric Acid SCHEMBL9566345 | 0.96 | KDM4E (0.93) | KDM4EALDH1A1GAAPDPK1KMT2A | |
| Hydrochloric Acid SCHEMBL4811305 | 0.96 | KDM4E (0.93) | KDM4EALDH1A1GAAPDPK1KMT2A | |
| Sulfuric Acid SCHEMBL9566343 | 0.91 | KDM4E (0.83) | KDM4EALDH1A1GAAPDPK1KMT2A | |
| SCHEMBL5746726 | 0.86 | ALDH1A1 (0.75) | KDM4EALDH1A1GAAPDPK1KMT2A | |
| SCHEMBL5749892 | 0.86 | ALDH1A1 (0.75) | KDM4EALDH1A1GAAPDPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116813617-A | Fluorescent probe based on naphthalimide-1, 4, 7-triazepan, preparation method and application thereof | 江汉大学 | 2023-09-29 | — | — | CN | disclosed |