Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.75 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.75 |
| ▸ | GAA | P10253 | 1/20 | 0.75 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | CASP1 | P29466 | 1/20 | 0.53 |
| ▸ | CASP7 | P55210 | 1/20 | 0.53 |
| ▸ | HBB | P68871 | 1/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | PLAU | P00749 | 2/20 | 0.46 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.42 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 8/20 | 0.41 |
| ▸ | PLK4 | O00444 | 1/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | ROS1 | P08922 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5746726 | 1.00 | ALDH1A1 (0.75) | ALDH1A1KDM4EGAACYP3A4HSD17B10 | |
| SCHEMBL497724 | 0.88 | KDM4E (0.96) | ALDH1A1KDM4EGAAHSD17B10PDPK1 | |
| SCHEMBL25192670 | 0.88 | KDM4E (0.96) | ALDH1A1KDM4EGAAHSD17B10PDPK1 | |
| SCHEMBL3502648 | 0.86 | KDM4E (0.62) | ALDH1A1KDM4EGAACYP3A4HSD17B10 | |
| Hydrochloric Acid SCHEMBL9566345 | 0.86 | KDM4E (0.93) | ALDH1A1KDM4EGAAHSD17B10PDPK1 | |
| Hydrochloric Acid SCHEMBL4811305 | 0.86 | KDM4E (0.93) | ALDH1A1KDM4EGAAHSD17B10PDPK1 | |
| SCHEMBL634215 | 0.86 | KDM4E (1.00) | ALDH1A1KDM4EGAAHSD17B10PDPK1 | |
| SCHEMBL29100415 | 0.86 | KDM4E (1.00) | ALDH1A1KDM4EGAAHSD17B10PDPK1 | |
| SCHEMBL29498815 | 0.86 | KDM4E (1.00) | ALDH1A1KDM4EGAAHSD17B10PDPK1 | |
| SCHEMBL30181949 | 0.86 | KDM4E (1.00) | ALDH1A1KDM4EGAAHSD17B10PDPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060293503-A1 | Polyaminopyridines and method for producing same | SUMITOMO SEIKA CHEMICALS CO., LTD (JP) | 2006-12-28 | — | — | US | disclosed |
| EP-1669390-A1 | POLYAMINOPYRIDINES AND METHOD FOR PRODUCING SAME | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 2006-06-14 | — | — | EP | disclosed |