SCHEMBL29100517

SCHEMBL29100517

OC(Br)(c1ccccc1)c1ccccc1Br

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
CA5A P35218 1/20 0.38
CA9 Q16790 1/20 0.38
CYP2C9 P11712 3/20 0.35
CYP1A2 P05177 3/20 0.35
CYP2C19 P33261 2/20 0.35
PTPN1 P18031 1/20 0.35
ALDH1A1 P00352 5/20 0.34
MAPK1 P28482 1/20 0.34
CRHBP P24387 1/20 0.34
CRHR2 Q13324 1/20 0.34
KCNN4 O15554 4/20 0.33
TSHR P16473 2/20 0.33
CYP2D6 P10635 1/20 0.32
HPGD P15428 1/20 0.32
HIF1A Q16665 1/20 0.32
HSD17B10 Q99714 1/20 0.32
HDAC3 O15379 1/20 0.32
HDAC4 P56524 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8784880 0.82 CRHBP (0.46) CA1CA2CA5ACA9CYP2C9
SCHEMBL3848016 0.80 ALDH1A1 (0.40) CA1CA2CA5ACA9CYP2C19
SCHEMBL11258329 0.80 CA1 (0.37) CA1CA2CA5ACA9CYP2C9
SCHEMBL4278139 0.77 CYP1A2 (0.46) CYP2C9CYP1A2CYP2C19PTPN1ALDH1A1
SCHEMBL14703697 0.76 CA1 (0.41) CA1CA2CA5ACA9ALDH1A1
SCHEMBL21763332 0.76 CA1 (0.41) CA1CA2CA5ACA9ALDH1A1
SCHEMBL6489437 0.76 CA1 (0.50) CA1CA2CA5ACA9PTPN1
SCHEMBL27772530 0.75 CA1 (0.43) CA1CA2CA5ACA9ALDH1A1
SCHEMBL27581558 0.75 CA1 (0.34) CA1CA2CA5ACA9CYP2C9
SCHEMBL9667701 0.75 CA1 (0.34) CA1CA2CA5ACA9CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114957692-B Hyperbranched polyphenyl and preparation method and application thereof 苏州大学 2023-08-11 CN disclosed