Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 18/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | CASP1 | P29466 | 2/20 | 0.51 |
| ▸ | CASP7 | P55210 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29701577 | 0.89 | ALDH1A1 (0.57) | ALDH1A1HSD17B10MAPK1TSHRCASP1 | |
| SCHEMBL29100739 | 0.89 | ALDH1A1 (0.57) | ALDH1A1HSD17B10MAPK1TSHRCASP1 | |
| SCHEMBL6250003 | 0.80 | ALDH1A1 (0.62) | ALDH1A1HSD17B10MAPK1TSHRCASP1 | |
| SCHEMBL29487159 | 0.80 | ALDH1A1 (0.62) | ALDH1A1HSD17B10MAPK1TSHRCASP1 | |
| SCHEMBL27180184 | 0.79 | ALDH1A1 (0.57) | ALDH1A1HSD17B10MAPK1TSHRCASP1 | |
| SCHEMBL2209684 | 0.78 | ALDH1A1 (0.67) | ALDH1A1HSD17B10MAPK1TSHRCASP1 | |
| SCHEMBL374339 | 0.78 | ALDH1A1 (0.67) | ALDH1A1HSD17B10MAPK1TSHRCASP1 | |
| SCHEMBL25284932 | 0.78 | ALDH1A1 (0.56) | ALDH1A1HSD17B10MAPK1TSHRCASP1 | |
| SCHEMBL30465757 | 0.78 | ALDH1A1 (0.56) | ALDH1A1HSD17B10MAPK1TSHRCASP1 | |
| SCHEMBL18451210 | 0.77 | ALDH1A1 (0.58) | ALDH1A1HSD17B10MAPK1TSHRCASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116981667-A | Heterocyclic inhibitors of EGFR and/or HER2 for cancer treatment | 蝎子疗法股份有限公司 | 2023-10-31 | — | — | CN | disclosed |
| EP-4225445-A2 | HETEROCYCLIC INHIBITORS OF EGFR AND/OR HER2, FOR USE IN THE TREATMENT OF CANCER | Scorpion Therapeutics, Inc. (US) | 2023-08-16 | — | — | EP | disclosed |
| WO-2022076831-A2 | METHODS FOR TREATING CANCER | SCORPION THERAPEUTICS, INC. (US) | 2022-04-14 | — | — | WO | disclosed |