Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 15/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | CASP7 | P55210 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | S100A9 | P06702 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25284932 | 1.00 | ALDH1A1 (0.56) | ALDH1A1HSD17B10MAPK1TSHRCYP1A2 | |
| SCHEMBL27180184 | 0.86 | ALDH1A1 (0.57) | ALDH1A1HSD17B10MAPK1TSHRCYP1A2 | |
| SCHEMBL29701577 | 0.86 | ALDH1A1 (0.57) | ALDH1A1HSD17B10MAPK1TSHRCYP1A2 | |
| SCHEMBL29100739 | 0.86 | ALDH1A1 (0.57) | ALDH1A1HSD17B10MAPK1TSHRCYP1A2 | |
| SCHEMBL2209684 | 0.78 | ALDH1A1 (0.67) | ALDH1A1HSD17B10MAPK1TSHRCYP1A2 | |
| SCHEMBL29100770 | 0.78 | ALDH1A1 (0.56) | ALDH1A1HSD17B10MAPK1TSHRCYP1A2 | |
| SCHEMBL15010761 | 0.77 | ALDH1A1 (0.62) | ALDH1A1HSD17B10MAPK1TSHRCYP1A2 | |
| SCHEMBL18451210 | 0.77 | ALDH1A1 (0.58) | ALDH1A1HSD17B10MAPK1TSHRCYP1A2 | |
| SCHEMBL30682699 | 0.77 | ALDH1A1 (0.58) | ALDH1A1HSD17B10MAPK1TSHRCYP1A2 | |
| SCHEMBL22323732 | 0.76 | ALDH1A1 (0.53) | ALDH1A1HSD17B10MAPK1TSHRCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4448510-A1 | INHIBITORS OF MET KINASE | Kinnate Biopharma Inc. (US) | 2024-10-23 | — | — | EP | disclosed |
| CN-118742542-A | Inhibitors of MET kinase | 金耐特生物制药公司 | 2024-10-01 | — | — | CN | disclosed |
| US-11753395-B2 | Inhibitors of MET kinase | KINNATE BIOPHARMA INC. (US) | 2023-09-12 | — | — | US | disclosed |
| WO-2023114809-A1 | INHIBITORS OF MET KINASE | KINNATE BIOPHARMA INC. (US) | 2023-06-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11753395-B2 | Inhibitors of MET kinase | MET, RET, MERTK | ALDH1A1 2071/4885HSD17B10 3607/4885MAPK1 555/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.