Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.42 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.42 |
| ▸ | RYR2 | Q92736 | 1/20 | 0.42 |
| ▸ | CD4 | P01730 | 2/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29101146 | 0.89 | KCNN4 (0.47) | HSD11B1MAPTMMP2KCNN4KCNA3 | |
| SCHEMBL29714451 | 0.86 | KCNN4 (0.54) | HSD11B1MAPTLMNAALDH1A1MMP2 | |
| SCHEMBL28836746 | 0.86 | KCNN4 (0.54) | HSD11B1MAPTLMNAALDH1A1MMP2 | |
| SCHEMBL29714461 | 0.83 | KCNN4 (0.48) | HSD11B1MAPTLMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL28836779 | 0.83 | KCNN4 (0.48) | HSD11B1MAPTLMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL30688098 | 0.82 | KCNN4 (0.56) | HSD11B1LMNASMN1; SMN2MMP2KCNN4 | |
| SCHEMBL29101134 | 0.82 | KCNN4 (0.56) | HSD11B1LMNASMN1; SMN2MMP2KCNN4 | |
| SCHEMBL29714455 | 0.79 | KCNN4 (0.44) | HSD11B1MAPTLMNAKDM4EKMT2A | |
| SCHEMBL29101138 | 0.79 | KCNN4 (0.44) | HSD11B1MAPTLMNAKMT2AMEN1 | |
| SCHEMBL29101141 | 0.79 | KCNN4 (0.44) | HSD11B1MAPTLMNAKDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114716374-B | 3-bit substituted dihydroquinoline derivative and preparation method thereof | 武汉工程大学 | 2023-11-07 | — | — | CN | disclosed |
| CN-114716374-A | 3-substituted dihydroquinoline derivative and preparation method thereof | 武汉工程大学 | 2022-07-08 | — | — | CN | disclosed |