Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27870034 | 0.85 | KDM4E (0.43) | KDM4EALDH1A1KMT2AGAAMAPT | |
| SCHEMBL5694172 | 0.82 | POLB (0.41) | KDM4EALDH1A1KMT2AGAAMEN1 | |
| SCHEMBL3245827 | 0.81 | POLB (0.42) | KDM4EALDH1A1KMT2AGAAMAPT | |
| SCHEMBL1123625 | 0.77 | KMT2A (0.43) | ALDH1A1KMT2AMAPTMEN1PKM | |
| SCHEMBL216889 | 0.75 | ALDH1A1 (0.56) | ALDH1A1KMT2AGAAMAPTMEN1 | |
| SCHEMBL30614582 | 0.73 | HTT (0.43) | KDM4EALDH1A1KMT2AMAPTCYP2C19 | |
| SCHEMBL29352125 | 0.70 | KMT2A (0.51) | KDM4EALDH1A1KMT2AGAAMAPT | |
| SCHEMBL4340669 | 0.70 | KMT2A (0.51) | KDM4EALDH1A1KMT2AGAAMAPT | |
| SCHEMBL11199689 | 0.68 | KDM4E (0.48) | KDM4EALDH1A1KMT2AGAAMAPT | |
| SCHEMBL28743018 | 0.67 | POLB (0.37) | KDM4EALDH1A1GAAMAPTCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111051327-B | Cyclic dinucleotides as anticancer agents | 百时美施贵宝公司 | 2023-11-03 | — | — | CN | disclosed |
| CN-116323630-A | Phospholipid compounds and uses thereof | 吉利德科学公司 | 2023-06-23 | — | — | CN | disclosed |