SCHEMBL4340669

SCHEMBL4340669

O=[N+]([O-])c1ncn(S(=O)(=O)c2cccc3cccnc23)n1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.51
MAPT P10636 3/20 0.51
MEN1 O00255 3/20 0.51
SMN1; SMN2 Q16637 1/20 0.51
PKM P14618 1/20 0.49
L3MBTL1 Q9Y468 1/20 0.47
GAA P10253 3/20 0.47
MAPK1 P28482 2/20 0.47
KDM4E B2RXH2 2/20 0.47
APOBEC3G Q9HC16 2/20 0.47
CA1 P00915 1/20 0.47
CA2 P00918 1/20 0.47
CA9 Q16790 1/20 0.47
PDE10A Q9Y233 1/20 0.47
TSHR P16473 2/20 0.46
TDP1 Q9NUW8 2/20 0.46
MDM4 O15151 1/20 0.46
NFKBIA P25963 1/20 0.46
OPRK1 P41145 1/20 0.46
MDM2 Q00987 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29352125 1.00 KMT2A (0.51) KMT2AMAPTMEN1SMN1; SMN2PKM
SCHEMBL5694172 0.76 POLB (0.41) KMT2AMEN1SMN1; SMN2L3MBTL1GAA
SCHEMBL11225129 0.72 MAPT (0.60) KMT2AMAPTMEN1SMN1; SMN2L3MBTL1
SCHEMBL29101321 0.70 KDM4E (0.57) KMT2AMAPTMEN1SMN1; SMN2PKM
SCHEMBL8916832 0.70 PKM (0.49) KMT2AMAPTMEN1SMN1; SMN2PKM
SCHEMBL1123625 0.69 KMT2A (0.43) KMT2AMAPTMEN1SMN1; SMN2PKM
SCHEMBL14919733 0.68 ALDH1A1 (0.73) KMT2AMAPTMEN1SMN1; SMN2PKM
SCHEMBL3245827 0.68 POLB (0.42) KMT2AMAPTMEN1SMN1; SMN2PKM
SCHEMBL5422444 0.67 L3MBTL1 (0.76) KMT2AMAPTMEN1SMN1; SMN2L3MBTL1
SCHEMBL26107557 0.67 L3MBTL1 (0.68) KMT2AMAPTMEN1SMN1; SMN2L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2014797-A2 Coating composition for interconnection part of electrode and plasma display panel including the same Samsung SDI Co., Ltd. (KR) 2009-01-14 EP claimed
US-20080303439-A1 Coating composition for interconnection part of electrode and plasma display panel including the same SAMSUNG SDI CO., LTD., A CORP. OF THE REPUBLIC OF KOREA (KR) 2008-12-11 US claimed
EP-2014797-A2 Coating composition for interconnection part of electrode and plasma display panel including the same Samsung SDI Co., Ltd. (KR) 2009-01-14 EP disclosed
US-20080303439-A1 Coating composition for interconnection part of electrode and plasma display panel including the same SAMSUNG SDI CO., LTD., A CORP. OF THE REPUBLIC OF KOREA (KR) 2008-12-11 US disclosed
US-5700785-A ADMINISTERING TO TREAT RETROVIRAL INFECTIONS TEMPLE UNIVERSITY - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) 1997-12-23 US disclosed
EP-0725563-A1 MARINE STRUCTURE J.C. HEMPEL'S SKIBSFARVE-FABRIK A/S (DK) 1996-08-14 EP disclosed
EP-0716856-A2 Therapeutic uses of 2',5'-oligoadenylate derivatives Temple University of the Commonwealth System of Higher Education (US) 1996-06-19 EP disclosed
WO-1995011592-A1 MARINE STRUCTURE J.C. HEMPEL'S SKIBSFARVE-FABRIK A/S (DK) 1995-05-04 WO disclosed
EP-0420872-A4 THERAPEUTIC USES OF 2',5'-OLIGOADENYLATE DERIVATIVES 1992-10-21 EP disclosed
EP-0420872-A1 THERAPEUTIC USES OF 2',5'-OLIGOADENYLATE DERIVATIVES. UNIV TEMPLE (US) 1991-04-10 EP disclosed
US-4859768-A Derivatives of 2', 5'-oligoadenylate and antiviral uses thereof TEMPLE UNIVERSITY OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) 1989-08-22 US disclosed