Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 8/20 | 0.53 |
| ▸ | KLK7 | P49862 | 4/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29101361 | 0.86 | KLK7 (0.50) | MEN1ALDH1A1KMT2AMAPTMAPK1 | |
| SCHEMBL3955546 | 0.86 | HDAC2 (0.51) | MEN1ALDH1A1KMT2AMAPTMAPK1 | |
| SCHEMBL11636534 | 0.82 | HDAC2 (0.56) | MEN1ALDH1A1KMT2AMAPTMAPK1 | |
| SCHEMBL3960647 | 0.81 | SIRT1 (0.59) | HDAC2KLK7 | |
| SCHEMBL29383934 | 0.80 | KCNH2 (0.45) | MEN1ALDH1A1KMT2AMAPTMAPK1 | |
| SCHEMBL5264997 | 0.78 | MEN1 (0.61) | MEN1ALDH1A1KMT2AMAPTMAPK1 | |
| SCHEMBL9267426 | 0.78 | MEN1 (0.61) | MEN1ALDH1A1KMT2AMAPTMAPK1 | |
| SCHEMBL11642274 | 0.78 | HDAC2 (0.62) | MEN1ALDH1A1KMT2AMAPTMAPK1 | |
| SCHEMBL7099035 | 0.77 | MEN1 (0.78) | MEN1ALDH1A1KMT2AMAPTMAPK1 | |
| SCHEMBL11644668 | 0.77 | HDAC2 (0.68) | MEN1ALDH1A1KMT2AMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114761079-B | Benzothiazepine compounds and their use as bile acid modulators | 阿尔比里奥公司 | 2024-05-28 | — | — | CN | disclosed |
| CN-117412955-A | Benzothiazepine compounds and their use as bile acid modulators | 阿尔比里奥公司 | 2024-01-16 | — | — | CN | disclosed |
| CN-116583504-A | Benzothiazepine compounds and their use as bile acid modulators | 阿尔比里奥公司 | 2023-08-11 | — | — | CN | disclosed |