Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC2 | Q92769 | 9/20 | 0.51 |
| ▸ | LTA4H | P09960 | 1/20 | 0.50 |
| ▸ | KLK7 | P49862 | 3/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 2/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | PLG | P00747 | 1/20 | 0.40 |
| ▸ | CALCRL | Q16602 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29101367 | 0.86 | MEN1 (0.54) | HDAC2KLK7HDAC3HDAC4HDAC1 | |
| SCHEMBL27037096 | 0.84 | HDAC2 (0.51) | HDAC2LTA4HKLK7HDAC3HDAC4 | |
| SCHEMBL3960647 | 0.81 | SIRT1 (0.59) | HDAC2KLK7 | |
| SCHEMBL13820164 | 0.78 | LTA4H (0.70) | HDAC2LTA4HPOLBMMP2MMP9 | |
| Hydrochloric Acid SCHEMBL14230868 | 0.77 | LTA4H (0.68) | HDAC2LTA4HHDAC8MMP2MMP9 | |
| SCHEMBL29101361 | 0.73 | KLK7 (0.50) | KLK7MEN1ALDH1A1MAPTMAPK1 | |
| SCHEMBL8741502 | 0.72 | HDAC2 (0.51) | HDAC2KLK7HDAC3HDAC4HDAC1 | |
| SCHEMBL29117249 | 0.72 | MMP3 (0.48) | MMP2MMP9KMT2A | |
| SCHEMBL8741546 | 0.72 | HDAC2 (0.51) | HDAC2KLK7HDAC3HDAC4HDAC1 | |
| SCHEMBL29117246 | 0.72 | MMP3 (0.48) | MMP2MMP9KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009026701-A1 | SIRTUIN INHIBITORS | METHYLGENE INC. (CA) | 2009-03-05 | — | — | WO | disclosed |