Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.36 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.35 |
| ▸ | TYR | P14679 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.35 |
| ▸ | MDM4 | O15151 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30688303 | 1.00 | LMNA (0.46) | LMNATRPA1PTGS1CACNA1CACHE | |
| SCHEMBL597121 | 0.80 | LMNA (0.46) | LMNATRPA1PTGS1CACNA1CACHE | |
| SCHEMBL11926272 | 0.77 | LMNA (0.52) | LMNATRPA1PTGS1CACNA1CKDM4E | |
| SCHEMBL30496179 | 0.74 | LMNA (0.50) | LMNATRPA1PTGS1CACNA1CKDM4E | |
| SCHEMBL8205772 | 0.74 | LMNA (0.50) | LMNATRPA1PTGS1CACNA1CKDM4E | |
| SCHEMBL27308320 | 0.73 | LMNA (0.44) | LMNATRPA1PTGS1CACNA1CACHE | |
| SCHEMBL12546195 | 0.73 | LMNA (0.47) | LMNATRPA1PTGS1CACNA1CKDM4E | |
| SCHEMBL14087383 | 0.70 | LMNA (0.52) | LMNAKDM4ESMN1; SMN2MAPTPABPC1 | |
| SCHEMBL13310639 | 0.70 | ELANE (0.55) | LMNAKDM4ESMN1; SMN2MAPTPABPC1 | |
| SCHEMBL31107058 | 0.70 | ELANE (0.55) | LMNAKDM4ESMN1; SMN2MAPTPABPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117003606-A | Preparation method of diene compound | 上海陶术生物科技有限公司 | 2023-11-07 | — | — | CN | disclosed |