Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP1 | O94782 | 2/20 | 0.47 |
| ▸ | WDR48 | Q8TAF3 | 2/20 | 0.47 |
| ▸ | MMP9 | P14780 | 3/20 | 0.41 |
| ▸ | MAOB | P27338 | 4/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.34 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.34 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.34 |
| ▸ | EDNRA | P25101 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5968665 | 1.00 | USP1 (0.47) | USP1WDR48MMP9MAOBP2RX7 | |
| SCHEMBL5160271 | 1.00 | USP1 (0.47) | USP1WDR48MMP9MAOBP2RX7 | |
| SCHEMBL6427211 | 1.00 | USP1 (0.47) | USP1WDR48MMP9MAOBP2RX7 | |
| SCHEMBL3762198 | 1.00 | USP1 (0.47) | USP1WDR48MMP9MAOBP2RX7 | |
| SCHEMBL7747416 | 0.83 | USP1 (0.44) | USP1WDR48MMP9MAOBP2RX7 | |
| SCHEMBL14543852 | 0.83 | USP1 (0.42) | USP1WDR48MMP9MAOBP2RX7 | |
| SCHEMBL7219023 | 0.83 | USP1 (0.42) | USP1WDR48MMP9MAOB | |
| SCHEMBL7227003 | 0.83 | USP1 (0.42) | USP1WDR48MMP9MAOB | |
| SCHEMBL8021171 | 0.83 | USP1 (0.42) | USP1WDR48MMP9MAOB | |
| SCHEMBL8036861 | 0.80 | TSHR (0.56) | USP1WDR48MEN1CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114195820-B | Isoserine derivative, preparation thereof and application thereof in taxol synthesis | 中山大学 | 2023-11-10 | — | — | CN | claimed |