Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP1 | O94782 | 1/20 | 0.42 |
| ▸ | WDR48 | Q8TAF3 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7227003 | 1.00 | USP1 (0.42) | USP1WDR48POLBCYP2D6MAOB | |
| SCHEMBL7219023 | 1.00 | USP1 (0.42) | USP1WDR48POLBCYP2D6MAOB | |
| SCHEMBL14543852 | 0.86 | USP1 (0.42) | USP1WDR48MAOBALDH1A1SMN1; SMN2 | |
| SCHEMBL7221650 | 0.85 | PDCD1 (0.42) | USP1WDR48MAOBALDH1A1MAPT | |
| SCHEMBL8036861 | 0.85 | TSHR (0.56) | USP1WDR48CYP2D6ALDH1A1SMN1; SMN2 | |
| SCHEMBL8036865 | 0.85 | TSHR (0.56) | USP1WDR48CYP2D6ALDH1A1SMN1; SMN2 | |
| SCHEMBL29101714 | 0.83 | USP1 (0.47) | USP1WDR48MAOBMMP9 | |
| SCHEMBL6427211 | 0.83 | USP1 (0.47) | USP1WDR48MAOBMMP9 | |
| SCHEMBL5968665 | 0.83 | USP1 (0.47) | USP1WDR48MAOBMMP9 | |
| SCHEMBL5160271 | 0.83 | USP1 (0.47) | USP1WDR48MAOBMMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6127546-A | Process for the preparation of oxazoline compound | DONG KOOK PHARMACEUTICAL CO., LTD. (KR) | 2000-10-03 | — | — | US | disclosed |