Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 known ✓ | P08172 | 2/20 | 0.36 |
| ▸ | CHRM4 known ✓ | P08173 | 2/20 | 0.36 |
| ▸ | CHRM1 known ✓ | P11229 | 2/20 | 0.36 |
| ▸ | CHRM5 known ✓ | P08912 | 1/20 | 0.35 |
| ▸ | CHRM3 known ✓ | P20309 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 7/20 | 0.36 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | BLM | P54132 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29102422 | 0.96 | LMNA (0.42) | MEN1KMT2ACYP2C19RECQLCYP1A2 | |
| Iodide SCHEMBL29102413 | 0.96 | MEN1 (0.40) | MEN1KMT2ACYP2C19RECQLCYP1A2 | |
| SCHEMBL561301 | 0.82 | TSHR (0.45) | SMN1; SMN2TSHRMAPK1TP53HIF1A | |
| SCHEMBL19469394 | 0.81 | LMNA (0.62) | MEN1KMT2ACYP2C19RECQLCYP1A2 | |
| SCHEMBL29405785 | 0.79 | MEN1 (0.65) | MEN1KMT2ACYP2C19RECQLCYP1A2 | |
| SCHEMBL22028173 | 0.79 | LMNA (0.60) | MEN1KMT2ACYP2C19RECQLCYP1A2 | |
| SCHEMBL288777 | 0.79 | MEN1 (0.65) | MEN1KMT2ACYP2C19RECQLCYP1A2 | |
| SCHEMBL17076330 | 0.79 | MEN1 (0.34) | MEN1KMT2ACYP2C19RECQLCYP1A2 | |
| Bromide SCHEMBL28073958 | 0.78 | TSHR (0.57) | MEN1KMT2ACYP2C19RECQLCYP1A2 | |
| SCHEMBL4632793 | 0.77 | TSHR (0.41) | MEN1KMT2ACYP2C19RECQLCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024254965-A1 | POLYELECTROLYTE GEL, PREPARATION METHOD THEREFOR AND USE THEREOF | 清华大学 | 2024-12-19 | — | — | WO | claimed |
| CN-117024774-A | Polyelectrolyte gel, preparation method and application thereof | 清华大学 | 2023-11-10 | — | — | CN | claimed |
| WO-2024254965-A1 | POLYELECTROLYTE GEL, PREPARATION METHOD THEREFOR AND USE THEREOF | 清华大学 | 2024-12-19 | — | — | WO | disclosed |
| CN-117024774-A | Polyelectrolyte gel, preparation method and application thereof | 清华大学 | 2023-11-10 | — | — | CN | disclosed |