Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 known ✓ | P08172 | 2/20 | 0.36 |
| ▸ | CHRM1 known ✓ | P11229 | 2/20 | 0.36 |
| ▸ | CHRM3 known ✓ | P20309 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 5/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | BLM | P54132 | 3/20 | 0.39 |
| ▸ | GALR3 | O60755 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.38 |
| ▸ | GMNN | O75496 | 3/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL29102419 | 0.96 | MEN1 (0.40) | LMNASMN1; SMN2MEN1KMT2ACYP2C19 | |
| Iodide SCHEMBL29102413 | 0.96 | MEN1 (0.40) | LMNASMN1; SMN2MEN1KMT2ACYP2C19 | |
| SCHEMBL561301 | 0.82 | TSHR (0.45) | SMN1; SMN2MAPK1TSHRTP53HIF1A | |
| SCHEMBL19469394 | 0.81 | LMNA (0.62) | LMNASMN1; SMN2MEN1KMT2ACYP2C19 | |
| SCHEMBL29405785 | 0.79 | MEN1 (0.65) | LMNASMN1; SMN2MEN1KMT2ACYP2C19 | |
| SCHEMBL22028173 | 0.79 | LMNA (0.60) | LMNASMN1; SMN2MEN1KMT2ACYP2C19 | |
| SCHEMBL288777 | 0.79 | MEN1 (0.65) | LMNASMN1; SMN2MEN1KMT2ACYP2C19 | |
| SCHEMBL17076330 | 0.79 | MEN1 (0.34) | LMNASMN1; SMN2MEN1KMT2ACYP2C19 | |
| Hydrochloric Acid SCHEMBL1238012 | 0.78 | MAPT (0.60) | LMNASMN1; SMN2MEN1KMT2ACYP2C19 | |
| Hydrochloric Acid SCHEMBL29013456 | 0.78 | MAPK1 (0.45) | LMNAMEN1KMT2ACYP2C19MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024254965-A1 | POLYELECTROLYTE GEL, PREPARATION METHOD THEREFOR AND USE THEREOF | 清华大学 | 2024-12-19 | — | — | WO | claimed |
| CN-117024774-A | Polyelectrolyte gel, preparation method and application thereof | 清华大学 | 2023-11-10 | — | — | CN | claimed |
| WO-2024254965-A1 | POLYELECTROLYTE GEL, PREPARATION METHOD THEREFOR AND USE THEREOF | 清华大学 | 2024-12-19 | — | — | WO | disclosed |
| CN-117024774-A | Polyelectrolyte gel, preparation method and application thereof | 清华大学 | 2023-11-10 | — | — | CN | disclosed |