Methane

Methane

SCHEMBL29102488

C.CC(C)(C)OC(=O)N1CCNCC1(C)C.F[B-](F)(F)F.F[B-](F)(F)F.F[B-](F)(F)F

nearest known ligand 0.38

Full drug profile on Sugi Atlas →

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CTSK P43235 1/20 0.33
USP2 O75604 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
MAPK1 P28482 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL324691 0.93 USP2 (0.38) CTSKUSP2SMN1; SMN2MAPK1
Hydrochloric Acid SCHEMBL18096129 0.91 USP2 (0.37) CTSKUSP2SMN1; SMN2MAPK1
SCHEMBL27121465 0.84 CTSK (0.39) CTSKUSP2SMN1; SMN2MAPK1
SCHEMBL38663950 0.79 USP2 (0.37) CTSKUSP2SMN1; SMN2MAPK1
SCHEMBL25694549 0.79 USP2 (0.37) CTSKUSP2SMN1; SMN2MAPK1
SCHEMBL25847564 0.78 USP2 (0.36) CTSKUSP2SMN1; SMN2MAPK1
SCHEMBL28724815 0.77 USP2 (0.38) CTSKUSP2SMN1; SMN2MAPK1
SCHEMBL16636874 0.77 USP2 (0.35) CTSKUSP2SMN1; SMN2MAPK1
SCHEMBL28670928 0.77 USP2 (0.35) CTSKUSP2SMN1; SMN2MAPK1
SCHEMBL5478401 0.77 USP2 (0.35) CTSKUSP2SMN1; SMN2MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116802182-A Pyrazolopyridine derivatives and uses thereof 诺华股份有限公司 2023-09-22 CN disclosed