Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 15/20 | 0.45 |
| ▸ | NR1H3 | Q13133 | 14/20 | 0.45 |
| ▸ | FPR3 | P25089 | 1/20 | 0.40 |
| ▸ | FPR2 | P25090 | 1/20 | 0.40 |
| ▸ | ESRRB | O95718 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ESRRA | P11474 | 1/20 | 0.39 |
| ▸ | ESRRG | P62508 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29104046 | 0.86 | NR1H2 (0.48) | NR1H2NR1H3FPR3FPR2ESRRB | |
| SCHEMBL29103995 | 0.83 | NR1H2 (0.42) | NR1H2NR1H3FPR3FPR2ESRRB | |
| SCHEMBL29104020 | 0.83 | NR1H2 (0.51) | NR1H2NR1H3ESRRBESR1ESRRA | |
| SCHEMBL29104051 | 0.83 | NR1H2 (0.51) | NR1H2NR1H3ESRRBESR1ESRRA | |
| SCHEMBL29104088 | 0.83 | NR1H2 (0.51) | NR1H2NR1H3ESRRBESR1ESRRA | |
| SCHEMBL25808763 | 0.83 | NR1H2 (0.51) | NR1H2NR1H3ESRRBESR1ESRRA | |
| SCHEMBL17784 | 0.79 | ALDH1A1 (0.39) | NR1H2KMT2A | |
| SCHEMBL29104026 | 0.79 | NR1H2 (0.51) | NR1H2NR1H3ESRRBESR1ESRRA | |
| SCHEMBL31111659 | 0.77 | NR1H2 (0.53) | NR1H2NR1H3ESRRBESR1ESRRA | |
| SCHEMBL18377007 | 0.77 | NR1H2 (0.53) | NR1H2NR1H3ESRRBESR1ESRRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117003755-A | Pyrazolopyridazinone derivatives, compositions and uses thereof | 北京伯汇生物技术有限公司 | 2023-11-07 | — | — | CN | disclosed |