Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 6/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.31 |
| ▸ | FPR2 | P25090 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29104038 | 1.00 | IGF1R (0.34) | IGF1RAKR1C3FPR2MAPT | |
| SCHEMBL29104065 | 0.79 | SLC6A2 (0.33) | IGF1RAKR1C3MAPT | |
| SCHEMBL29104061 | 0.79 | SLC6A2 (0.33) | IGF1RAKR1C3MAPT | |
| SCHEMBL29104070 | 0.72 | MAPT (0.38) | AKR1C3MAPT | |
| SCHEMBL29104074 | 0.72 | MAPT (0.38) | AKR1C3MAPT | |
| SCHEMBL29104107 | 0.69 | SLC6A2 (0.33) | AKR1C3FPR2MAPT | |
| SCHEMBL29104105 | 0.69 | SLC6A2 (0.33) | AKR1C3FPR2MAPT | |
| SCHEMBL29104082 | 0.68 | AKR1C3 (0.41) | IGF1RAKR1C3FPR2MAPT | |
| SCHEMBL12323814 | 0.68 | SPHK2 (0.38) | — | |
| SCHEMBL29104056 | 0.68 | MAPT (0.40) | AKR1C3FPR2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117003755-A | Pyrazolopyridazinone derivatives, compositions and uses thereof | 北京伯汇生物技术有限公司 | 2023-11-07 | — | — | CN | disclosed |