Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TRPC6 | Q9Y210 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | FPR2 | P25090 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.35 |
| ▸ | IGF1R | P08069 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28094591 | 0.87 | AKR1C3 (0.40) | AKR1C3MAPTNPSR1ALDH1A1GAA | |
| SCHEMBL23887667 | 0.86 | GFER (0.44) | MAPTNPSR1ALDH1A1TRPC6GAA | |
| SCHEMBL21877154 | 0.86 | AKR1C3 (0.41) | AKR1C3TRPC6OPRK1AGTR2DRD2 | |
| SCHEMBL23887664 | 0.86 | GFER (0.44) | MAPTNPSR1ALDH1A1TRPC6GAA | |
| SCHEMBL21877157 | 0.86 | AKR1C3 (0.41) | AKR1C3TRPC6OPRK1AGTR2DRD2 | |
| SCHEMBL29104044 | 0.85 | AKR1C3 (0.39) | AKR1C3MAPTNPSR1ALDH1A1GAA | |
| SCHEMBL29104058 | 0.85 | MAPT (0.40) | AKR1C3MAPTNPSR1ALDH1A1TRPC6 | |
| SCHEMBL29104056 | 0.85 | MAPT (0.40) | AKR1C3MAPTNPSR1ALDH1A1TRPC6 | |
| SCHEMBL29104034 | 0.84 | DRD2 (0.43) | AKR1C3MAPTNPSR1ALDH1A1TRPC6 | |
| SCHEMBL29104036 | 0.84 | DRD2 (0.43) | AKR1C3MAPTNPSR1ALDH1A1TRPC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117003755-A | Pyrazolopyridazinone derivatives, compositions and uses thereof | 北京伯汇生物技术有限公司 | 2023-11-07 | — | — | CN | disclosed |