Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | ESRRB | O95718 | 5/20 | 0.32 |
| ▸ | ESRRG | P62508 | 5/20 | 0.32 |
| ▸ | MAPT | P10636 | 5/20 | 0.32 |
| ▸ | IGF1R | P08069 | 1/20 | 0.32 |
| ▸ | PPARD | Q03181 | 2/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD4 | P21917 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ESRRA | P11474 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29104065 | 1.00 | SLC6A2 (0.33) | SLC6A2SLC6A4AKR1C3ESRRBESRRG | |
| SCHEMBL29104105 | 0.87 | SLC6A2 (0.33) | SLC6A2SLC6A4AKR1C3MAPTKDM4E | |
| SCHEMBL29104107 | 0.87 | SLC6A2 (0.33) | SLC6A2SLC6A4AKR1C3MAPTKDM4E | |
| SCHEMBL29104074 | 0.80 | MAPT (0.38) | SLC6A2SLC6A4AKR1C3ESRRBESRRG | |
| SCHEMBL29104070 | 0.80 | MAPT (0.38) | SLC6A2SLC6A4AKR1C3ESRRBESRRG | |
| SCHEMBL29104038 | 0.79 | IGF1R (0.34) | AKR1C3MAPTIGF1R | |
| SCHEMBL29104041 | 0.79 | IGF1R (0.34) | AKR1C3MAPTIGF1R | |
| SCHEMBL24504308 | 0.73 | ALDH1A1 (0.53) | SLC6A2SLC6A4MAPTIGF1RDRD2 | |
| SCHEMBL29104082 | 0.70 | AKR1C3 (0.41) | SLC6A2SLC6A4AKR1C3MAPTIGF1R | |
| SCHEMBL29104044 | 0.70 | AKR1C3 (0.39) | SLC6A2SLC6A4AKR1C3MAPTDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117003755-A | Pyrazolopyridazinone derivatives, compositions and uses thereof | 北京伯汇生物技术有限公司 | 2023-11-07 | — | — | CN | disclosed |