Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | GAPDH | P04406 | 1/20 | 0.38 |
| ▸ | HSPA1A | P0DMV8 | 1/20 | 0.38 |
| ▸ | HSPA8 | P11142 | 1/20 | 0.38 |
| ▸ | CD44 | P16070 | 1/20 | 0.38 |
| ▸ | MSN | P26038 | 1/20 | 0.38 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.38 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28174910 | 0.88 | ALDH1A1 (0.50) | ALDH1A1MAPTSMN1; SMN2HTTLMNA | |
| SCHEMBL27972715 | 0.79 | TSHR (0.37) | TDP1SMN1; SMN2KDM4EHSP90AA1KMT2A | |
| SCHEMBL30912584 | 0.79 | ALDH1A1 (0.44) | ALDH1A1TDP1CYP3A4MAPTSMN1; SMN2 | |
| SCHEMBL28153044 | 0.76 | HSPA1A (0.42) | ALDH1A1TDP1CYP3A4ALOX15MAPT | |
| SCHEMBL29456504 | 0.74 | HSD17B10 (0.42) | ALDH1A1MAPTSMN1; SMN2HTTLMNA | |
| SCHEMBL31472329 | 0.74 | HSD17B10 (0.42) | ALDH1A1MAPTSMN1; SMN2HTTLMNA | |
| SCHEMBL21491367 | 0.74 | HSD17B10 (0.42) | ALDH1A1MAPTSMN1; SMN2HTTLMNA | |
| SCHEMBL28288786 | 0.73 | ALDH1A1 (0.45) | ALDH1A1TDP1CYP3A4ALOX15MAOA | |
| SCHEMBL22123315 | 0.73 | ALDH1A1 (0.57) | ALDH1A1TDP1CYP3A4ALOX15MAOA | |
| SCHEMBL28923834 | 0.71 | ALDH1A1 (0.47) | ALDH1A1TDP1CYP3A4ALOX15MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115645543-A | Maytansinoid derivatives, conjugates thereof, and methods of use | 里珍纳龙药品有限公司 | 2023-01-31 | — | — | CN | disclosed |