Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.33 |
| ▸ | WDR5 | P61964 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2909904 | 0.92 | CYP3A4 (0.40) | CYP3A4CRBNADRB1WDR5 | |
| SCHEMBL2914330 | 0.91 | CYP3A4 (0.40) | CYP3A4CRBNADRB1WDR5 | |
| SCHEMBL2910588 | 0.91 | CYP3A4 (0.40) | CYP3A4CRBNADRB1WDR5 | |
| SCHEMBL2906898 | 0.91 | CYP3A4 (0.40) | CYP3A4CRBNADRB1WDR5 | |
| SCHEMBL2913880 | 0.85 | CYP3A4 (0.56) | CYP3A4CRBN | |
| SCHEMBL2913728 | 0.85 | CYP3A4 (0.56) | CYP3A4CRBN | |
| SCHEMBL2915916 | 0.82 | CRBN (0.39) | CYP3A4CRBNADRB1WDR5 | |
| SCHEMBL2910562 | 0.82 | HPGD (0.41) | CYP3A4CRBNADRB1 | |
| SCHEMBL1530128 | 0.82 | CYP3A4 (0.40) | CYP3A4CRBNADRB1WDR5 | |
| SCHEMBL10254310 | 0.82 | CYP3A4 (0.40) | CYP3A4CRBNADRB1WDR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2222646-A1 | URACIL OR THYMINE DERIVATIVE FOR TREATING HEPATITIS C | Abbott Laboratories (US) | 2010-09-01 | — | — | EP | disclosed |
| EP-2203430-A1 | N-PHENYL-DIOXO-HYDROPYRIMIDINES USEFUL AS HEPATITIS C VIRUS (HCV) INHIBITORS | Abbott Laboratories (US) | 2010-07-07 | — | — | EP | disclosed |
| WO-2009039135-A1 | N-PHENYL-DIOXO-HYDROPYRIMIDINES USEFUL AS HEPATITIS C VIRUS (HCV) INHIBITORS | ABBOTT LABORATORIES (US) | 2009-03-26 | — | — | WO | disclosed |
| WO-2009039127-A1 | URACIL OR THYMINE DERIVATIVE FOR TREATING HEPATITIS C | ABBOTT LABORATORIES (US) | 2009-03-26 | — | — | WO | disclosed |