Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE1B | Q01064 | 1/20 | 0.35 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 3/20 | 0.32 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29695127 | 1.00 | PDE1B (0.35) | PDE1BDGAT1DPP4JMJD6ALDH1A1 | |
| SCHEMBL29108175 | 0.87 | PDE1B (0.35) | PDE1BDGAT1DPP4JMJD6 | |
| SCHEMBL30640096 | 0.83 | PDE1B (0.31) | PDE1BDGAT1 | |
| SCHEMBL31161564 | 0.80 | DGAT1 (0.40) | PDE1BDGAT1JMJD6ALDH1A1MAPT | |
| SCHEMBL30640188 | 0.80 | PDE1B (0.30) | PDE1B | |
| SCHEMBL29694852 | 0.79 | — | — | |
| SCHEMBL29694980 | 0.78 | — | — | |
| SCHEMBL30741539 | 0.76 | AGBL2 (0.39) | DPP4JMJD6ALDH1A1LMNAMAPT | |
| SCHEMBL25219283 | 0.71 | HCAR2 (0.46) | PDE1BDPP4ALDH1A1LMNAMAPT | |
| SCHEMBL30481154 | 0.71 | HCAR2 (0.46) | PDE1BDPP4ALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117083271-A | Substituted thiadiazolyl derivatives as DNA polymerase theta inhibitors | 伊迪亚生物科学有限公司 | 2023-11-17 | — | — | CN | disclosed |