Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 4/20 | 0.73 |
| ▸ | GLO1 | Q04760 | 4/20 | 0.63 |
| ▸ | ABL1 | P00519 | 1/20 | 0.63 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.62 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.62 |
| ▸ | MAOA | P21397 | 2/20 | 0.62 |
| ▸ | MAOB | P27338 | 2/20 | 0.62 |
| ▸ | IKBKB | O14920 | 1/20 | 0.59 |
| ▸ | CHUK | O15111 | 1/20 | 0.59 |
| ▸ | IKBKG | Q9Y6K9 | 1/20 | 0.59 |
| ▸ | NFKB1 | P19838 | 4/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.59 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.59 |
| ▸ | RELA | Q04206 | 3/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.59 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.59 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.59 |
| ▸ | STAT3 | P40763 | 2/20 | 0.59 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.59 |
| ▸ | KDM1A | O60341 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL79945 | 0.94 | GLO1 (0.71) | SNCAGLO1ABL1ABCB1AKR1B1 | |
| SCHEMBL2403631 | 0.90 | GLO1 (0.67) | SNCAGLO1ABL1ABCB1AKR1B1 | |
| SCHEMBL7194289 | 0.81 | SNCA (0.88) | SNCAGLO1ABL1ABCB1AKR1B1 | |
| SCHEMBL17019805 | 0.79 | CYP2D6 (0.88) | SNCAGLO1ABL1ABCB1AKR1B1 | |
| Ferulate SCHEMBL5189434 | 0.79 | SNCA (0.91) | SNCAGLO1ABL1ABCB1AKR1B1 | |
| Ferulate SCHEMBL31310232 | 0.79 | SNCA (0.91) | SNCAGLO1ABL1ABCB1AKR1B1 | |
| SCHEMBL29642906 | 0.79 | CYP2D6 (0.77) | SNCAGLO1ABL1ABCB1AKR1B1 | |
| SCHEMBL31621191 | 0.79 | CYP2D6 (0.77) | SNCAGLO1ABL1ABCB1AKR1B1 | |
| SCHEMBL29711883 | 0.78 | GLO1 (0.67) | SNCAGLO1ABL1ABCB1AKR1B1 | |
| SCHEMBL15228430 | 0.78 | MAPT (0.68) | SNCAGLO1ABL1ABCB1AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2195421-B1 | POLYPEPTIDES HAVING ACETYLXYLAN ESTERASE ACTIVITY AND POLYNUCLEOTIDES ENCODING SAME | NOVOZYMES AS (DK) | 2015-09-16 | — | — | EP | disclosed |
| EP-2224822-A1 | POLYPEPTIDES HAVING ACETYLXYLAN ESTERASE ACTIVITY AND POLYNUCLEOTIDES ENCODING SAME | Novozymes A/S (DK) | 2010-09-08 | — | — | EP | disclosed |
| WO-2009073709-A1 | POLYPEPTIDES HAVING ACETYLXYLAN ESTERASE ACTIVITY AND POLYNUCLEOTIDES ENCODING SAME | NOVOZYMES A/S (DK) | 2009-06-11 | — | — | WO | disclosed |