SCHEMBL79945

SCHEMBL79945

COc1cc(C=CC(=O)C([C]=O)=Cc2ccc(O)c(OC)c2)ccc1O

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GLO1 Q04760 5/20 0.71
ABL1 P00519 1/20 0.71
IKBKB O14920 2/20 0.67
CHUK O15111 2/20 0.67
IKBKG Q9Y6K9 2/20 0.67
NFKB1 P19838 3/20 0.63
CYP2D6 P10635 3/20 0.63
CYP1A2 P05177 2/20 0.63
ALOX5 P09917 2/20 0.63
HSD11B1 P28845 2/20 0.63
STAT3 P40763 2/20 0.63
NFKB2 Q00653 2/20 0.63
RELA Q04206 2/20 0.63
NFE2L2 Q16236 2/20 0.63
SNCA P37840 4/20 0.63
APP P05067 3/20 0.62
KDM4E B2RXH2 2/20 0.62
CA12 O43570 2/20 0.62
CA1 P00915 2/20 0.62
CA2 P00918 2/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2403631 0.96 GLO1 (0.67) GLO1ABL1IKBKBCHUKIKBKG
SCHEMBL2910901 0.94 SNCA (0.73) GLO1ABL1IKBKBCHUKIKBKG
SCHEMBL15228430 0.83 MAPT (0.68) GLO1ABL1IKBKBCHUKIKBKG
SCHEMBL7686675 0.83 KDM4E (0.56) NFKB1CYP1A2ALOX5SNCAAPP
SCHEMBL29642906 0.82 CYP2D6 (0.77) GLO1ABL1IKBKBCHUKIKBKG
SCHEMBL31621191 0.82 CYP2D6 (0.77) GLO1ABL1IKBKBCHUKIKBKG
SCHEMBL29711883 0.81 GLO1 (0.67) GLO1ABL1IKBKBCHUKIKBKG
SCHEMBL23817770 0.80 GLO1 (1.00) GLO1ABL1IKBKBCHUKIKBKG
SCHEMBL30497483 0.80 GLO1 (0.87) GLO1ABL1IKBKBCHUKIKBKG
SCHEMBL7585369 0.80 GLO1 (0.87) GLO1ABL1IKBKBCHUKIKBKG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 94 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10072280-B2 Compositions for saccharification of cellulosic material NOVOZYMES, INC. (US) 2018-09-11 US disclosed
US-10006012-B2 Polypeptides having cellulolytic enhancing activity and polynucleotides encoding same NOVOZYMES, INC. (US) 2018-06-26 US disclosed
US-9663772-B2 Aspergillus fumigatus cellulolytic enzyme compositions and uses thereof NOVOZYMES, INC. (US) 2017-05-30 US disclosed
US-20170145457-A1 Compositions for saccharification of cellulosic material UNITED STATES DEPARTMENT OF ENERGY 2017-05-25 US disclosed
US-9611463-B2 Cellobiohydrolase variants and polynucleotides encoding same NOVOZYMES, INC. (US) 2017-04-04 US disclosed
US-9587262-B2 Compositions for saccharification of cellulosic material NOVOZYMES, INC. (US) 2017-03-07 US disclosed
US-9512416-B2 Endoglucanase variants CODEXIS, INC. (US) 2016-12-06 US disclosed
US-9441214-B2 Polypeptide having beta-glucosidase activity and uses thereof DSM IP ASSETS B.V. (NL) 2016-09-13 US disclosed
US-9410136-B2 Methods for enhancing the degradation or conversion of cellulosic material NOVOZYMES, INC. (US) 2016-08-09 US disclosed
US-9371551-B2 Methods for enhancing the degradation of cellulosic material with chitin binding proteins NOVOZYMES, INC. (US) 2016-06-21 US disclosed
US-20110020873-A1 Biomass Hydrolysis Process NOVOZYMES A/S (DK) 2011-01-27 US disclosed
WO-2011008785-A2 A METHOD OF ANALYZING CELLULOSE DECAY IN CELLULOSIC MATERIAL HYDROLYSIS NOVOZYMES A/S (DK) 2011-01-20 WO disclosed
EP-2274322-A1 POLYPEPTIDES HAVING FERULIC ACID ESTERASE ACTIVITY AND POLYNUCLEOTIDES ENCODING SAME Novozymes A/S (DK) 2011-01-19 EP disclosed
US-20110010805-A1 Polypeptides having cellulolytic enhancing activity and polynucleotides encoding same NOVOZYMES A/S (DK) 2011-01-13 US disclosed
WO-2011005867-A1 POLYPEPTIDES HAVING CELLULOLYTIC ENHANCING ACTIVITY ACTIVITY AND POLYNUCLEOTIDES ENCODING SAME NOVOZYMES, INC. (US) 2011-01-13 WO disclosed
US-7868227-B2 Polypeptides having cellulolytic enhancing activity and polynucleotides encoding same NOVOZYMES, INC. (US) 2011-01-11 US disclosed
WO-2011000949-A1 TALAROMYCES STRAINS AND ENZYME COMPOSITIONS DSM IP ASSETS B.V. (NL) 2011-01-06 WO disclosed
WO-2011002832-A1 BIOMASS HYDROLYSIS PROCESS NOVOZYMES A/S (DK) 2011-01-06 WO disclosed
EP-2268804-A1 HEMICELLULASE ENRICHED COMPOSITIONS FOR ENHANCING HYDROLYSIS OF BIOMASS Danisco US Inc. (US) 2011-01-05 EP disclosed
US-20100281582-A1 Polypeptides having xylanase activity and polynucleotides encoding same NOVOZYMES, INC. (US) 2010-11-04 US disclosed