Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | HCAR3 | P49019 | 3/20 | 0.55 |
| ▸ | CDC25B | P30305 | 1/20 | 0.54 |
| ▸ | DTYMK | P23919 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | AKR1C3 | P42330 | 5/20 | 0.45 |
| ▸ | AKR1C2 | P52895 | 5/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | CTSV | O60911 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.41 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8900476 | 0.90 | HCAR3 (0.59) | MAPTHCAR3CDC25BDTYMKHTT | |
| SCHEMBL13948943 | 0.90 | HCAR3 (0.59) | MAPTHCAR3CDC25BDTYMKHTT | |
| SCHEMBL671475 | 0.85 | MAPT (0.55) | MAPTHCAR3CDC25BDTYMKHTT | |
| SCHEMBL11697530 | 0.83 | DTYMK (0.60) | MAPTHCAR3DTYMKTSHRALDH1A1 | |
| SCHEMBL11641794 | 0.82 | MAPT (0.55) | MAPTHCAR3CDC25BHTTAKR1C3 | |
| SCHEMBL27669664 | 0.81 | HCAR3 (0.45) | MAPTHCAR3CDC25BDTYMKHTT | |
| SCHEMBL13911185 | 0.81 | MAPT (0.53) | MAPTHCAR3CDC25BHTTAKR1C3 | |
| SCHEMBL2824822 | 0.80 | DTYMK (0.44) | MAPTHCAR3CDC25BDTYMKAKR1C3 | |
| SCHEMBL2824819 | 0.80 | DTYMK (0.44) | MAPTHCAR3CDC25BDTYMKAKR1C3 | |
| SCHEMBL26628821 | 0.80 | PDGFRB (0.49) | MAPTHCAR3CDC25BHTTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116648250-A | Novel quinazoline derivatives as SOS1 inhibitors and uses thereof | 韩美药品株式会社 | 2023-08-25 | — | — | CN | disclosed |