Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 9/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | CDC25B | P30305 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.45 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | DTYMK | P23919 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29109409 | 0.90 | MAPT (0.59) | HCAR3MAPTCDC25BHTTAKR1C3 | |
| SCHEMBL13948943 | 0.86 | HCAR3 (0.59) | HCAR3MAPTCDC25BHTTAKR1C3 | |
| SCHEMBL671475 | 0.85 | MAPT (0.55) | HCAR3MAPTCDC25BHTTAKR1C3 | |
| SCHEMBL670410 | 0.85 | HCAR3 (0.55) | HCAR3MAPTCDC25BHTTAKR1C3 | |
| SCHEMBL7371713 | 0.85 | HCAR3 (0.55) | HCAR3MAPTCDC25BHTTAKR1C3 | |
| SCHEMBL23578454 | 0.85 | HCAR3 (0.55) | HCAR3MAPTCDC25BHTTAKR1C3 | |
| SCHEMBL9898957 | 0.85 | HCAR3 (0.55) | HCAR3MAPTCDC25BHTTAKR1C3 | |
| SCHEMBL15323319 | 0.83 | PDGFRB (0.49) | HCAR3MAPTCDC25BHTTAKR1C3 | |
| SCHEMBL1724987 | 0.83 | HCAR3 (0.52) | HCAR3MAPTCDC25BHTTAKR1C3 | |
| SCHEMBL11641794 | 0.82 | MAPT (0.55) | HCAR3MAPTCDC25BHTTAKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5686482-A | DOPAMINE RECEPTOR ANTAGONIST | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1997-11-11 | — | — | US | disclosed |
| EP-0757985-A1 | N-(3-PYRROLIDINYL)BENZAMIDE DERIVATIVE | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1997-02-12 | — | — | EP | disclosed |