Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TAS2R14 | Q9NYV8 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | SYK | P43405 | 3/20 | 0.38 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15635649 | 0.82 | TAS2R14 (0.42) | KDM4EALDH1A1LMNATAS2R14NPC1 | |
| SCHEMBL15638568 | 0.80 | TLR7 (0.44) | KDM4EALDH1A1LMNATAS2R14NPC1 | |
| SCHEMBL14319639 | 0.79 | KDM6B (0.47) | KDM4EALDH1A1TAS2R14NPC1RAB9A | |
| SCHEMBL15635192 | 0.78 | TAS2R14 (0.43) | LMNATAS2R14NPC1RAB9AGAA | |
| SCHEMBL24761059 | 0.77 | TAS2R14 (0.44) | KDM4EALDH1A1LMNATAS2R14NPC1 | |
| SCHEMBL5063130 | 0.77 | KDM6B (0.45) | KDM4EALDH1A1CA12CA9 | |
| SCHEMBL15639327 | 0.77 | TAS2R14 (0.42) | KDM4EALDH1A1LMNATAS2R14NPC1 | |
| SCHEMBL15638939 | 0.76 | TLR7 (0.45) | LMNATAS2R14NPC1RAB9AGAA | |
| SCHEMBL19371823 | 0.76 | NPC1 (0.40) | KDM4EALDH1A1SMN1; SMN2LMNATAS2R14 | |
| SCHEMBL6218067 | 0.75 | ACLY (0.44) | LMNATAS2R14NPC1RAB9AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116903613-A | 2-oxo quinazoline five-membered heterocyclic derivative, preparation method and application thereof | 深圳微芯生物科技股份有限公司 | 2023-10-20 | — | — | CN | disclosed |