Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | AR | P10275 | 2/20 | 0.40 |
| ▸ | KDM5A | P29375 | 1/20 | 0.40 |
| ▸ | FABP4 | P15090 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | SHMT2 | P34897 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30611217 | 1.00 | ALDH1A1 (0.41) | ALDH1A1MEN1KMT2AHPGDKDM4E | |
| SCHEMBL13622759 | 0.76 | KDM4E (0.57) | KMT2AKDM4ESHMT2 | |
| SCHEMBL11591796 | 0.76 | ADORA1 (0.53) | ALDH1A1MEN1KMT2AKDM4EKDM5A | |
| SCHEMBL11721081 | 0.73 | ALDH1A1 (0.50) | ALDH1A1MEN1KMT2AHPGDKDM4E | |
| SCHEMBL30039796 | 0.73 | HPGD (0.40) | ALDH1A1HPGDARFABP4MAPT | |
| SCHEMBL30549011 | 0.73 | HPGD (0.40) | ALDH1A1HPGDARFABP4MAPT | |
| SCHEMBL4351926 | 0.73 | TRPV1 (0.44) | ALDH1A1HPGDPOLB | |
| SCHEMBL30611322 | 0.73 | GRIN2D (0.67) | MEN1KMT2AKDM4EGAAPOLB | |
| SCHEMBL29110302 | 0.73 | GRIN2D (0.67) | MEN1KMT2AKDM4EGAAPOLB | |
| SCHEMBL30499843 | 0.72 | ALDH1A1 (0.41) | ALDH1A1MEN1KMT2AHPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116903613-A | 2-oxo quinazoline five-membered heterocyclic derivative, preparation method and application thereof | 深圳微芯生物科技股份有限公司 | 2023-10-20 | — | — | CN | disclosed |