Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.40 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29110316 | 0.85 | TLR7 (0.47) | NPC1RAB9AACSS2MAOAMAOB | |
| SCHEMBL3438307 | 0.82 | RAB9A (0.50) | NPC1RAB9AMEN1KMT2ATDP1 | |
| SCHEMBL17448068 | 0.80 | KLKB1 (0.37) | MEN1KMT2AACSS2ALDH1A1IRAK4 | |
| SCHEMBL26983072 | 0.78 | HDAC8 (0.38) | NPC1RAB9AALDH1A1IRAK4SMN1; SMN2 | |
| SCHEMBL25402055 | 0.77 | HDAC6 (0.59) | NPC1RAB9ATDP1POLBALDH1A1 | |
| SCHEMBL6838478 | 0.77 | KDM5A (0.46) | NPC1RAB9AMEN1KMT2ATDP1 | |
| SCHEMBL17453073 | 0.76 | NPC1 (0.34) | NPC1RAB9AMEN1KMT2APOLB | |
| SCHEMBL25402755 | 0.76 | HCAR3 (0.49) | NPC1RAB9AMEN1KMT2ATDP1 | |
| SCHEMBL6840368 | 0.76 | KDM4E (0.47) | NPC1RAB9AMEN1KMT2ATDP1 | |
| SCHEMBL28274082 | 0.76 | IRAK4 (0.47) | NPC1RAB9AMEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116903613-A | 2-oxo quinazoline five-membered heterocyclic derivative, preparation method and application thereof | 深圳微芯生物科技股份有限公司 | 2023-10-20 | — | — | CN | disclosed |