SCHEMBL29110487

SCHEMBL29110487

N#Cc1cc(C#N)c(C#N)c(-c2cccc3cc4ccccc4cc23)c1C#N

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 3/20 0.38
CA2 P00918 3/20 0.38
MCL1 Q07820 1/20 0.38
PIM1 P11309 2/20 0.37
KDM4E B2RXH2 4/20 0.36
CES1 P23141 1/20 0.35
CLK1 P49759 1/20 0.35
DYRK1A Q13627 1/20 0.35
USP8 P40818 1/20 0.34
USP7 Q93009 1/20 0.34
ALDH1A1 P00352 5/20 0.33
GAA P10253 2/20 0.33
NCOA3 Q9Y6Q9 1/20 0.33
PDE9A O76083 1/20 0.33
MAP2K2 P36507 1/20 0.33
MAP2K1 Q02750 1/20 0.33
ANPEP P15144 1/20 0.33
HTT P42858 1/20 0.33
HPGD P15428 2/20 0.33
TSHR P16473 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29110490 0.87 MCL1 (0.49) CA1CA2MCL1PIM1KDM4E
SCHEMBL29489130 0.81 MCL1 (0.47) CA1CA2MCL1PIM1KDM4E
SCHEMBL28228483 0.80 CA1 (0.46) CA1CA2MCL1PIM1KDM4E
SCHEMBL769609 0.75 CA1 (0.46) CA1CA2MCL1PIM1KDM4E
SCHEMBL31050902 0.75 CA1 (0.52) CA1CA2MCL1KDM4ECLK1
SCHEMBL32172 0.75 CA1 (0.52) CA1CA2MCL1KDM4ECLK1
SCHEMBL31050903 0.75 CA1 (0.52) CA1CA2MCL1KDM4ECLK1
SCHEMBL13985609 0.75 MCL1 (0.38) CA1CA2MCL1PIM1KDM4E
SCHEMBL444302 0.74 CA1 (0.47) CA1CA2PIM1KDM4ECLK1
SCHEMBL30858824 0.73 CA1 (0.50) CA1CA2MCL1KDM4ECLK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117089083-A Method for synthesizing low-dimensional heterostructure based on cascade charge transfer organic alloy design 江西善拓环境科技有限公司 2023-11-21 CN disclosed