SCHEMBL29110490

SCHEMBL29110490

N#Cc1cc(C#N)c(C#N)c(-c2cccc3ccccc23)c1C#N

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MCL1 Q07820 1/20 0.49
CA1 P00915 2/20 0.47
CA2 P00918 2/20 0.47
KDM4E B2RXH2 4/20 0.47
PIM1 P11309 5/20 0.45
ALOX15 P16050 3/20 0.41
ANPEP P15144 1/20 0.40
STK10 O94804 1/20 0.39
SLK Q9H2G2 1/20 0.39
ALDH1A1 P00352 3/20 0.39
CYP11B1 P15538 1/20 0.38
CYP11B2 P19099 1/20 0.38
MEN1 O00255 1/20 0.38
HCRTR1 O43613 1/20 0.38
GLA P06280 1/20 0.38
POLB P06746 1/20 0.38
GAA P10253 1/20 0.38
HPGD P15428 1/20 0.38
TSHR P16473 1/20 0.38
ALOX12 P18054 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29489130 0.90 MCL1 (0.47) MCL1CA1CA2KDM4EPIM1
SCHEMBL29110487 0.87 CA1 (0.38) MCL1CA1CA2KDM4EPIM1
SCHEMBL29152139 0.80 KDM4E (0.50) MCL1CA1CA2KDM4EPIM1
SCHEMBL769553 0.79 CA1 (0.55) MCL1CA1CA2KDM4EPIM1
SCHEMBL13170778 0.79 CA1 (0.55) MCL1CA1CA2KDM4EPIM1
SCHEMBL29039496 0.79 CA1 (0.50) MCL1CA1CA2KDM4EPIM1
SCHEMBL15535538 0.79 MCL1 (0.43) MCL1CA1CA2KDM4EPIM1
SCHEMBL20561064 0.78 MCL1 (0.58) MCL1CA1CA2KDM4EPIM1
SCHEMBL31236642 0.78 MCL1 (0.58) MCL1CA1CA2KDM4EPIM1
SCHEMBL28813070 0.78 KDM4E (0.67) KDM4EPIM1ALOX15ALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117089083-A Method for synthesizing low-dimensional heterostructure based on cascade charge transfer organic alloy design 江西善拓环境科技有限公司 2023-11-21 CN disclosed