Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 4/20 | 0.62 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.62 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.62 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.62 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.62 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.62 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.62 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.62 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.62 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.62 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.62 |
| ▸ | NCOR2 | Q9Y618 | 3/20 | 0.62 |
| ▸ | MEN1 | O00255 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29110822 | 0.86 | HDAC3 (0.58) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL29110824 | 0.84 | HDAC3 (0.53) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL13586958 | 0.77 | MEN1 (0.73) | MEN1KMT2APOLBGAARAB9A | |
| SCHEMBL13586959 | 0.76 | MEN1 (0.71) | MEN1KMT2APOLBGAARAB9A | |
| SCHEMBL26306785 | 0.73 | SMN1; SMN2 (0.57) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL29110757 | 0.73 | HDAC6 (0.71) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL29110804 | 0.72 | HDAC6 (0.67) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL29606448 | 0.72 | HDAC6 (0.67) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL4245233 | 0.71 | LOXL2 (0.65) | GAAMAPTTDP1ALDH1A1HPGD | |
| SCHEMBL7720244 | 0.71 | MAPT (0.51) | HDAC1MEN1KMT2APOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114621194-B | 4-methylene-N-hydroxybenzoamide compound and application thereof | 沈阳药科大学 | 2023-08-29 | — | — | CN | disclosed |
| CN-114621194-A | 4-methylene-N-hydroxybenzamide compound and application thereof | 沈阳药科大学 | 2022-06-14 | — | — | CN | disclosed |