Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | CASP6 | P55212 | 1/20 | 0.37 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30142174 | 1.00 | ALDH1A1 (0.47) | ALDH1A1HTTMAPK1MEN1KMT2A | |
| SCHEMBL29112115 | 0.81 | ALDH1A1 (0.47) | ALDH1A1HTTMAPK1MEN1KMT2A | |
| SCHEMBL29818534 | 0.79 | ALDH1A1 (0.68) | ALDH1A1HTTMAPK1MEN1KMT2A | |
| SCHEMBL25193455 | 0.79 | ALDH1A1 (0.68) | ALDH1A1HTTMAPK1MEN1KMT2A | |
| SCHEMBL24759988 | 0.79 | CNR2 (0.41) | ALDH1A1MEN1KMT2AHPGDL3MBTL1 | |
| SCHEMBL29818809 | 0.77 | CNR2 (0.40) | ALDH1A1HTTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL25197838 | 0.77 | CNR2 (0.40) | ALDH1A1HTTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL85570 | 0.75 | POLB (0.55) | ALDH1A1HTTMAPK1MEN1KMT2A | |
| SCHEMBL10077046 | 0.73 | MAPT (0.61) | ALDH1A1MEN1KMT2AKDM4EGAA | |
| SCHEMBL3544112 | 0.72 | ALDH1A1 (0.56) | ALDH1A1HTTMAPK1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117120427-A | MALT1 inhibitor and preparation method and application thereof | 上海拓界生物医药科技有限公司 | 2023-11-24 | — | — | CN | disclosed |