Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.41 |
| ▸ | MTOR | P42345 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | CASP6 | P55212 | 1/20 | 0.35 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.35 |
| ▸ | SCD | O00767 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30142174 | 0.81 | ALDH1A1 (0.47) | ALDH1A1HTTMAPK1MEN1KMT2A | |
| SCHEMBL29112112 | 0.81 | ALDH1A1 (0.47) | ALDH1A1HTTMAPK1MEN1KMT2A | |
| SCHEMBL25316526 | 0.80 | ALDH1A1 (0.63) | ALDH1A1HTTMAPK1TRPV1GAA | |
| SCHEMBL29475561 | 0.80 | ALDH1A1 (0.63) | ALDH1A1HTTMAPK1TRPV1GAA | |
| SCHEMBL24759998 | 0.80 | MTOR (0.43) | MEN1KMT2ATRPV1MTORLRRK2 | |
| SCHEMBL17293066 | 0.76 | ALDH1A1 (0.48) | ALDH1A1HTTMAPK1TRPV1MAPT | |
| SCHEMBL17292997 | 0.74 | ALDH1A1 (0.55) | ALDH1A1HTTMAPK1MEN1KMT2A | |
| SCHEMBL29818385 | 0.74 | ALDH1A1 (0.55) | ALDH1A1HTTMAPK1MEN1KMT2A | |
| SCHEMBL18787775 | 0.74 | ALDH1A1 (0.46) | ALDH1A1HTTMAPK1TRPV1MAPT | |
| SCHEMBL85649 | 0.73 | POLB (0.50) | ALDH1A1HTTMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117120427-A | MALT1 inhibitor and preparation method and application thereof | 上海拓界生物医药科技有限公司 | 2023-11-24 | — | — | CN | disclosed |