Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 11/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.39 |
| ▸ | TYK2 | P29597 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2910530 | 0.87 | TAAR1 (0.39) | AKR1B1SLC22A12MEN1KMT2A | |
| SCHEMBL271277 | 0.86 | RORC (0.39) | RORCAKR1B1PTGS2SLC22A12TYK2 | |
| SCHEMBL4002424 | 0.85 | TAAR1 (0.38) | AKR1B1SLC22A12MEN1KMT2A | |
| SCHEMBL271669 | 0.83 | RORC (0.38) | RORCPTGS2SLC22A12TYK2L3MBTL1 | |
| SCHEMBL2906762 | 0.81 | AKR1B1 (0.50) | AKR1B1SLC22A12SMN1; SMN2MEN1KMT2A | |
| SCHEMBL2903593 | 0.81 | HSD11B1 (0.45) | RORCAKR1B1PTGS2SLC22A12MEN1 | |
| SCHEMBL4004824 | 0.79 | HSD11B1 (0.44) | RORCAKR1B1PTGS2SLC22A12MEN1 | |
| Hydrochloric Acid SCHEMBL28259955 | 0.79 | AKR1B1 (0.48) | AKR1B1SLC22A12SMN1; SMN2MEN1KMT2A | |
| SCHEMBL12812210 | 0.78 | TAAR1 (0.41) | RORCAKR1B1PTGS2TYK2L3MBTL1 | |
| SCHEMBL2908977 | 0.77 | NOTUM (0.39) | AKR1B1SLC22A12SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2220056-B1 | HERBICIDAL COMPOUNDS | SYNGENTA LTD (GB) | 2015-09-30 | — | — | EP | disclosed |
| US-20100323889-A1 | HERBICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2010-12-23 | — | — | US | disclosed |
| EP-2220056-A1 | HERBICIDAL COMPOUNDS | Syngenta Limited (GB) | 2010-08-25 | — | — | EP | disclosed |
| WO-2009063180-A1 | HERBICIDAL COMPOUNDS | SYNGENTA LIMITED (GB) | 2009-05-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100323889-A1 | HERBICIDAL COMPOUNDS | CBR3, DDT, CBR1 | RORC 3066/4885AKR1B1 73/4885PTGS2 1536/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.