Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.44 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.41 |
| ▸ | FPR3 | P25089 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29112390 | 1.00 | HSD11B1 (0.54) | HSD11B1HTTATMTAS1R3TAS1R1 | |
| SCHEMBL24540861 | 1.00 | HSD11B1 (0.54) | HSD11B1HTTATMTAS1R3TAS1R1 | |
| SCHEMBL29141636 | 0.86 | HSD11B1 (0.52) | HSD11B1HTTATMTAS1R3TAS1R1 | |
| SCHEMBL24540601 | 0.85 | POLB (0.38) | HSD11B1HTTATMSMN1; SMN2ALDH1A1 | |
| SCHEMBL29112510 | 0.84 | KDM4E (0.40) | HSD11B1SMN1; SMN2ALDH1A1TDP1MEN1 | |
| SCHEMBL24540862 | 0.84 | KDM4E (0.40) | HSD11B1SMN1; SMN2ALDH1A1TDP1MEN1 | |
| SCHEMBL29112514 | 0.84 | KDM4E (0.40) | HSD11B1SMN1; SMN2ALDH1A1TDP1MEN1 | |
| SCHEMBL24540251 | 0.84 | GAA (0.44) | SMN1; SMN2ALDH1A1LMNAGAANPC1 | |
| SCHEMBL29112470 | 0.84 | GAA (0.44) | SMN1; SMN2ALDH1A1LMNAGAANPC1 | |
| SCHEMBL29112469 | 0.84 | GAA (0.44) | SMN1; SMN2ALDH1A1LMNAGAANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116829532-A | Substituted cyclohexane carboxamides, their preparation and their therapeutic use | 赛诺菲 | 2023-09-29 | — | — | CN | disclosed |