Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 10/20 | 0.41 |
| ▸ | CA2 | P00918 | 10/20 | 0.41 |
| ▸ | CA12 | O43570 | 4/20 | 0.41 |
| ▸ | CA9 | Q16790 | 4/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | AAK1 | Q2M2I8 | 3/20 | 0.40 |
| ▸ | BRD4 | O60885 | 2/20 | 0.40 |
| ▸ | STK17B | O94768 | 1/20 | 0.38 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31410591 | 0.83 | MEN1 (0.43) | MEN1GAAKMT2AIDO1CA1 | |
| SCHEMBL25496751 | 0.83 | GAA (0.55) | MEN1GAAKMT2ACA1CA2 | |
| SCHEMBL25496760 | 0.81 | MEN1 (0.50) | MEN1GAAKMT2ACA1CA2 | |
| SCHEMBL3649756 | 0.80 | GAA (0.55) | MEN1GAAKMT2AIDO1CA1 | |
| SCHEMBL25496756 | 0.80 | GAA (0.55) | MEN1GAAKMT2AIDO1CA1 | |
| SCHEMBL25496750 | 0.79 | MEN1 (0.56) | MEN1GAAKMT2ACA1CA2 | |
| SCHEMBL25496770 | 0.79 | GAA (0.50) | MEN1GAAKMT2ACA1CA2 | |
| SCHEMBL28630946 | 0.79 | MEN1 (0.50) | MEN1GAAKMT2AIDO1CA1 | |
| SCHEMBL25496038 | 0.79 | GAA (0.50) | MEN1GAAKMT2ACA1CA2 | |
| SCHEMBL25496775 | 0.79 | HDAC1 (0.51) | MEN1GAAKMT2ACA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117120090-A | HPK1 antagonists and uses thereof | 林伯士萨顿公司 | 2023-11-24 | — | — | CN | disclosed |